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The Food and Drug Administration, FDA, has approved the drug Vivitrol for that treatment of opioid dependence according to a news release by them on 10-12-2010.

Using two separate drugs to lose weight can be very effective there are combinations before the FDA now awaiting approval. When dealing with weight reduction and the people that go through it you need to err along the side of caution and allow the FDA do its job and demand some research be done so the public is aware of the side effects and perils associated with the medications before we drive them. Keep in mind that drug companies have been in business to generate money and that they would say anything to keep people on his or her medications.

Researchers discovered that participants taking this drug for any year, lost excess weight within one month and have kept the extra weight off through the entire 56 weeks of the study. Contrave can be a combination of the drugs naltrexone and bupropion, which generally seems to reflect a fresh trend of weight-loss drugs which might be made up of multiple active ingredient, which may make them more efficient and safer.

Combo-pilling is the newest fad or in addition to this the newest in the future under scrutiny and for that reason it is just more publicly known in recent months, comb-pilling for losing weight has been around since the eighties. The biggest reason that by using a combination of pills is now popular is the fact that by right now there aren't long term prescription diet pills that have been approved by the FDA aside from orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications and some of the combinations are actually rejected or have yet to be approved by the FDA.

Seizures really are a side effect with Contrave and shouldn't be taken in people with seizure disorders. The drug could also raise blood pressure levels and heartbeat, and shouldn't be used in people with a history of cardiac arrest or stroke in the earlier six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy while using drug.

The FDA also warned that Contrave can raise blood pressure level and pulse rate and must not be used in patients with uncontrolled high blood pressure, as well as by you are not heart-related and cerebrovascular (blood vessel dysfunction impacting mental performance) disease. Patients using a history of heart attack or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes which has a boxed warning to alert medical researchers and patients on the increased likelihood of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for stop smoking.


The most common negative effects with Contrave include nausea, constipation, headache, vomiting, dizziness, insomnia, dry mouth, and diarrhea.